Armodafinil VS Adderall: Comparison


Armodafinil (Nuvigil) is similar to Adderall in that they can both improve wakefulness and alertness. However, they work differently in the brain and affect different chemicals. They are also classified as controlled medications differently.

What is Armodafinil?

armodafinil 50 mg tablet
The compound of the eugeroic modafinil known as armodafinil is enantiopure. One enantiomer of racemic modafinil is all that is present. The United States Food and Drug Administration authorised the use of armodafinil in June 2007. Cephalon Inc., a pharmaceutical company, manufactures it.

What is Adderral?

Adderall 30 mg
Four different amphetamine salts are combined in a medication known as mixed amphetamine salts, which is sold under the brand names Adderall and Mydayis. Racemic amphetamine and dextroamphetamine are both present in equal amounts in the combination, which results in a ratio between the amphetamine enantiomers levoamphetamine and dextroamphetamine.

Differences between Armodafinil and Adderral

They have several active components.
Armodafinil, the R-enantiomer of modafinil, is a component of Nuvigil (known by the brand name Provigil). Enantiomers, or a pair of molecules that are mirror images of one another, are armodafinil and modafinil.
Dextroamphetamine and amphetamine salts are also included in Adderall. Dextroamphetamine saccharide, dextroamphetamine sulphate, amphetamine aspartate, and amphetamine sulphate are the specific ingredients of Adderall. They use various formulas.

Currently, oral tablets of Nuvigil in dosages of 50 mg, 150 mg, 200 mg, and 250 mg are accessible. Oral tablets with the dosages of 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg, 20 mg, and 30 mg are available for the medication Adderall. Additionally, Adderall is offered as an extended-release tablet known as Adderall XR, which comes in dosages of 5, 10, 15, 20, 25, and 30 mg.

Various misuse dangers exist with them. The Drug Enforcement Agency has listed Nuvigil as a Schedule IV restricted drug (DEA). It is considered illegal to use Adderall and is listed on Schedule II. Therefore, there is less chance of misuse with Nuvigil than with Adderall. When these medicines are abused, especially when not used as directed, physical or psychological dependency may develop.

Various dosages are used. Every day, one dose of Nuvigil is typical. For Adderall to work, however, it may be necessary to take it up to twice or three times daily.

DRUG CLASSsimilar to a stimulant

agent that encourages alertness

Who typically uses the medication?Adults and young adults 17 years and olderAdults and children 3 years and older
What is the standard dosage?








For obstructive sleep apnea or narcolepsy:

150 to 250 mg once per day in the morning

For shift work disorder:

150 mg once per day 1 hour before starting work shift


5 mg once or twice daily. Dosage may be increased by 5 mg in weekly intervals

For narcolepsy:

5 to 60 mg per day in divided doses

Dosage may vary depending on the age of the person

How long is the typical treatment?Long term or as directed by a physicianLong term or as directed by a physician
What form(s) does the drug come in?       Oral tabletOral tablet
Brand/generic statusBrand and generic version availableBrand and generic version available

Is Adderall or Nuvigil more efficient?

Both Adderall and Nuvigil are powerful narcolepsy medications when compared to placebo. There aren’t many, if any, research comparing the efficacy of Nuvigil and Adderall directly.

Daytime-sleepiness and Adderal
The Provigil, Adderall, and Ritalin active components have been used to treat excessive daytime drowsiness, according to one research. In patients who are severely sick, stimulants, particularly modafinil, may aid in accelerating recovery and reducing tiredness. While medicines like Nuvigil and Adderall are useful for treating sleep issues, there are also other options that are readily available and being explored.

Adderall’s half-life is shorter than that of Nuvigil (15 hours versus 10 to 14 hours). Since Nuvigil has a longer half-life than Adderall, its effects are felt for a longer period of time. Nuvigil simply needs to be taken once, whereas Adderall may need to be taken several times during the day.

Before using a medication like Nuvigil or Adderall, like with any medications, it’s crucial to see a healthcare professional.

Nuvigil and Adderall coverage and price comparison:

Typically, brand-name drugs like Nuvigil are not covered by health insurance policies. As an alternative, some plans could pay for the drug’s generic equivalent. The average cost of 30 250 mg pills of Nuvigil without insurance is $1,120. It may be possible to reduce the price of Nuvigil to about $40 by using a savings tool like the SingleCare discount card.

Since a generic version of Adderall is available, it is typically not covered as a brand-name medication. The majority of insurance and Medicare programmers will assist in paying for the generic version. For 30 pills of 20 mg Adderall, the average retail price is $315. The price might be reduced to about $15 using an Adderall SingleCare discount card.

Typically covered by insurance?Yes, the genericYes, the generic
Typically covered by Medicare Part D?Yes, the genericYes, the generic
Quantity30, 250 mg tablets30, 20 mg tablets
Typical Medicare copay$15–$217$7–$78
SingleCare cost$40+$15+

Armodafinil (Nuvigil) is similar to Adderall in the way that they both can improve wakefulness and alertness. However, they work differently in the brain and affect different chemicals. They are also classified as controlled medications differently.

Some common side-effects of Armodafinil and Adderall:


  • The skin flaking, blistering, burning, crusting, or being dry.
  • Breathing that is difficult or laborious.
  • A heartbeat or pulse that beats quickly, unevenly, pounding, or rapidly.
  • Urinary frequency
  • A very painful and severe headache
  • Paler, watery urine in a larger volume.
  • Skin that is itchy, scaling, very red, painful, or swollen



  • Loss of appetite
  • Weight loss
  • Dry mouth
  • Discomfort or pain in the stomach
  • Nausea/vomiting headache dizziness fever diarrhea fever and anxiety
  • There may be issues with sleeping.









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About the author
Greg Nicholl
Greg Nicholl, CEO
Greg has over 20 years of experience in the pharmaceutical industry. They hold a Masters Degree in Urology. Greg uses their expertise to create informative and engaging content for
Greg can be reached via email at [email protected]

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