Nuvigil vs Provigil

Many people are confused as if Modafinil and Provigil are two different medicines (when it comes to narcolepsy treatment) even though they are two different medicines of the same formula only the names are different, but it should be known that Armodafinil can be called Nuvigil or Modafinil can also be called as Provigil. When it comes to compare Nuvigil and Provigil (Nuvigil vs Provigil) there are a few difference between the two and we have tried to clarify them in this blog.

What is Nuvigil (Armodafinil)?

Eugeroic modafinil has an enantiopure molecule called armodafinil (Nuvigil). Only the racemic modafinil enantiomer is present in it. The U.S. Food and Drug Administration gave armodafinil (Nuvigil) its seal of approval in June 2007 and Cephalon Inc. is the manufacturer.

What is Provigil (Modafinil)?

Narcolepsy, shift work sleep disorder, and obstructive sleep apnea is three conditions that can cause excessive daytime drowsiness. Modafinil (Provigil), a central nervous system stimulant drug, is one such example and is marketed under the trade name Provigil.

Comparison:

Does Nuvigil have more potency than Provigil?

Is modafinil (Provigil) superior to armodafinil (Nuvigil)? The efficacy and safety of modafinil (Provigil) and armodafinil (Nuvigil) are comparable. Over the day, armodafinil (Nuvigil) levels may rise in the body, though. In comparison to modafinil (Provigil), armodafinil’s (Nuvigil) effects could last longer.

What class does Provigil belong to?

Medications in the stimulant family include Provigil. It is offered in oral tablet dosages of 100 mg and 200 mg. According to studies, those who suffer from narcolepsy, sleep apnea, or shift work sleep disorder might stay up longer while using Provigil compared to a placebo.

What class does Nuvigil belong to?

Modafinil’s sole isomer, Nuvigil (armodafinil), is a stimulant. It is unclear what exactly causes the effect. Eugeroics are a class of medications that are stimulants that offer sustained mental stimulation, and armodafinil is one of these drugs.

Does Nuvigil help you Focus?

Your ability to concentrate, think, and act differently can be affected by armodafinil (Nuvigil). Even though the drug can increase alertness, some extremely sleepy people may still find it difficult to stay awake while using armodafinil (Nuvigil).

Does Provigil help you focus?

According to the research, the Researchers concluded that modafinil (Provigil)is more likely to aid boost attention and learning for more complicated thinking processes than for simple activities after reviewing 24 studies that looked into the usage of the drug in healthy, non-sleep-deprived adults.

Dosage Of Nuvigil For Obstructive Sleep Apnea And Narcolepsy (OSA):

For people with OSA or narcolepsy, NUVIGIL should be taken orally once daily in a single dose in the morning at a dose of 150 mg – 250 mg.

While doses up to 250 mg/day have been tolerated well [see CLINICAL PHARMACOLOGY and Clinical Studies], there is no compelling proof that dosages higher than 150 mg/day, given as a single dose, provide any significant advantages beyond those provided by the 150 mg/day dose in OSA patients.

A single oral dose of 150 mg of NUVIGIL should be administered daily to SWD patients, ideally an hour before the start of their shift.

Sticking to your doctor’s dosage recommendations and not over the highest dose permitted is pivotal.

Dosage of Provigil for Narcolepsy and Obstructed Sleep Apnea:

It is recommended that people with OSA or narcolepsy take a single dose of 200 mg of PROVIGIL /per day.

Although single doses up to 400 mg/day have been well tolerated [see CLINICAL PHARMACOLOGY and Clinical Studies], there is no trustworthy evidence that this dosage provides any additional benefits over 200 mg/day of dosage.

For people with SWD, a single oral dose of PROVIGIL 200 mg should be given once daily, about an hour before the patient’s shift.

Following your doctor’s dosage advice and not exceeding the maximum dosage allowed are crucial.

Benefits of Nuvigil:

When a person has narcolepsy, obstructive sleep apnea, or a shift work issue, they may use the drug Armodafinil (Nuvigil) to help them.

Among the possible advantages of Nuvigil, are:

• Escalating restraint and wakefulness
• Enhancing cognitive function
• Reducing unnecessarily long days of sleep
• Boosting the general quality of life for individuals suffering from sleep disorders

Benefits of Provigil

Various studies have demonstrated that when compared to a placebo, Provigil (modafinil) tends to increase the capacity of an individual with narcolepsy, sleep apnea, or a shift work sleep disorder to simply stay awake. Provigil is frequently the first medication to treat these disorders and lowering fatigue.

Precautions to take with Nuvigil (Armodafinil)

You shouldn’t take Nuvigil if you have ever had an allergic reaction or rash brought on Nuvigil. Immediately stop taking Nuvigil and call your physician if you notice any skin sensitivity, no matter how slight.

Provigil (Modafinil) Precautions to take:

There is a slight chance that this medication will trigger skin reactions. If while taking this medication you experience blistering, peeling, or loosening of the skin, red skin lesions, rasher, stop taking it immediately and see your doctor.

Major similarities between Provigil and Nuvigil?

Provigil and Nuvigil may help adults who have a documented tendency to drowsiness during the day feel more alert and awake. These medications are not meant to treat sleep disorders or serve as a substitute for getting enough sleep. In headache, their respective mechanisms of action, the drugs Provigil and Nuvigil are majorly similar since both of them work as cognitive enhancers, according to Provigil and Nuvigil reviews

Side-effects of Nuvigil:

The following worsens might appear headache, nausea, dry mouth, anxiety, vertigo, or trouble sleeping. Inform your doctor or pharmacist immediately if any of these symptoms persist or worsen. You should keep in mind that your doctor recommended this drug because she or he thought it would benefit you more than it would harm you.

Side-effects of Provigil:

• Headache
• Nausea.
• A sensation of unease.
• Anxiety.
• Difficulty sleeping
• Decrease in appetite
• Dizziness

Is Nuvigil Better than Provigil?

The brand names of the generic medication armodafinil and modafinil are Nuvigil and Provigil, respectively. Narcolepsy, sleep apnea, and shift work sleep disorder are all conditions that are treated with both medications. Nuvigil, on the other hand, is the R-enantiomer of modafinil, whereas Provigil is a racemic mixture of the R- and S-enantiomers. More research is required to confirm however,  some studies that claim the R-enantiomer may be more useful for treating conditions like narcolepsy. The side effects and precautions for both medications are similar.

References for Nuvigil vs Provigil:

WHAT IS NUVIGIL?

https://en.wikipedia.org/wiki/Armodafinil

WHAT IS PROVIGIL?

https://en.wikipedia.org/wiki/Modafinil

CLASS OF PROVIGIL

https://www.medicalnewstoday.cHELPticles/325963

CLASS OF NUVIGIL

https://www.medicalnewstoday.com/articles/325963

DOES NUVIGIL HELP YOU FOCUS?

https://www.goodrx.com/armodafinil/what-is

DOES PROVIGIL HELP YOU FOCUS?

https://www.drugs.com/slideshow/modafinil-facts-1253

DOSAGE OF NUVIGIL

https://www.rxlist.com/nuvigil-drug.htm#dosage

DOSAGE OF PROVIGIL

https://www.rxlist.com/provigil-drug.htm#dosage

BENEFITS OF NUVIGIL

https://www.goodrx.com/armodafinil/what-is

BENEFIT OF PROVIGIL

https://www.medicalnewstoday.com/articles/325963

PRECAUTIONS FOR NUVIGIL

https://www.drugs.com/nuvigil.html

PRECAUTIONS FOR PROVIGIL

https://www.mayoclinic.org/drugs-supplements/modafinil-oral-route/precautions/drg-20064870?p=1

SIDE-EFFECTS OF NUVIGIL

https://www.webmd.com/drugs/2/drug-152275/nuvigil-oral/details

SIDE-EFFECTS OF PROVIGIL

https://www.medicalnewstoday.com/articles/325963

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The information on the website, including but not limited to text, graphics, photos, and other content, is only meant to be used as informational material. Nothing on this website should be construed as professional medical advice or as any kind of therapy. It is always advisable to obtain professional medical advice from a licensed expert. If you want to try a new medical procedure, you should always see a doctor beforehand. When experiencing any negative effects or pain, get medical attention right once.

Product Comparison – Armodafinil Vs Modafinil

 Many of you people in this universe might be confused on what is the difference between Armodafinil and Modafinil. In this article we will try to understand that better (Armodafinil vs Modafinil)

What is Armodafinil?

The compound of the eugeroic modafinil known as armodafinil is enantiopure. One enantiomer of racemic modafinil is all that is present. The United States Food and Drug Administration authorised the use of armodafinil in June 2007. Cephalon Inc., a pharmaceutical company, manufactures it.

What is Modafinil?

Modafinil, sold under the brand name Provigil among others, is a central nervous system stimulant medication used to treat sleepiness due to narcolepsy, shift work sleep disorder, and obstructive sleep apnea.

Differences (Armodafinil vs Modafinil)

Compared to modafinil, armodafinil may have a longer half-life (brand-name Provigil). Armodafinil could be viewed in some situations as a more potent substance with superior benefits on alertness. Even if the negative effects of both medications can be identical, some side effects may be more prevalent in one medication than the other.

Can Armodafinil or modafinil get you higher?

Armodafinil is not associated with this “high” feeling. It works on excessive daytime sleepiness. ArmodafinilL only treats the symptom of sleepiness.

Though the Physicians’ Desk Reference warns that modafinil can cause the psychoactive and euphoric effects typical of central nervous system stimulant drugs3, and there is controversy surrounding its abuse potential, it appears to have very low abuse liability (low reinforcing effects) in non-drug users.

Can you take armodafinil and modafinil together?

Well, It is uncommon to use modafinil and armodafinil together. Similar active components can be found in both armodafinil and modafinil. Combining armodafinil with modafinil may raise the possibility of negative consequences.

Can Armodafinil make you tired?

Even though the drug can increase alertness, some people who are extremely sleepy may still find it difficult to stay awake while using armodafinil (Nuvigil). Until you know how this drug affects you, use caution and refrain from tasks that call for alertness, such as operating machinery or an automobile.

Can Modafinil make you tired?

Some people who use modafinil may feel lightheaded, sleepy, have difficulties thinking or managing their actions, or have trouble seeing properly. Before driving, operating machinery, or performing other tasks that call on you to be attentive, well-coordinated, or able to think or see clearly, be sure you are aware of how this medication affects you.

Why is my Modafinil Not Working?

Your modafinil could not be effective for a few different reasons. Depending on whether new users or seasoned users are encountering them, they may be divided into two groups.

1. New Users of Modafinil Have Problems

Have you used modafinil a few times and discovered it doesn’t provide the boost you were expecting when you bought it?

Before looking for a replacement nootropic, there are a few things you may attempt, but it’s first crucial to comprehend why it could not be functioning in the first place.

1. A) Modafinil of Poor Quality

Depending on where you obtained your modafinil, you could have received subpar medication that has no impact.

This is the cause, which is more typical than you may imagine.

How can we fix this problem?

The easiest solution is to acquire a fresh batch of modafinil pills from a reliable supplier if you believe your original batch was defective. Alternately, you might attempt to test it on a buddy to see if it works or not.

Thin Layer Chromatography is the most effective method for determining whether a medicine is active or not (TLC).

You may create your own TLC testing kits to check for the active ingredients if you’re very determined (not for the faint of heart).

If you want to give it a try, we advise using this DIY TLC test kit.

Precautions you should take for Armodafinil

If, while taking this medication, you have a rash, itching, blistering, peeling, or loosening of the skin, a fever or chills, chest pain, difficulty breathing, difficulty swallowing, or any swelling of the hands, face, mouth, or throat, call your doctor straight once.

Precautions you should take for Modafinil.

Serious skin reactions can occur with this medicine. Stop using this medicine and check with your doctor right away if you have blistering, peeling, or loosening of the skin; red skin lesions; severe acne or skin rash; sores or ulcers on the skin; or fever or chills while you are using this medicine.Serious skin reactions can occur with this medicine. Stop using this medicine and check with your doctor right away if you have blistering, peeling, or loosening of the skin; red skin lesions; severe acne or skin rash; sores or ulcers on the skin; or fever or chills while you are using this medicine.

Some similarities between Armodafinil and modafinil

In order to treat sleep disturbances, both Modafinil and Armodafinil are employed. Narcolepsy, shift work disorder, and obstructive sleep apnea are among the conditions for which they are most frequently employed. They try to make you more awake. Prescription drugs have a number of commonalities with comparable objectives.

Minimal chance of dependency

Both pharmaceuticals are under the IV drug classification, which is distinguished by a minimal risk of misuse and dependency. The likelihood of establishing an addiction is minimal because these drugs are non-narcotic. Since they are restricted substances that may only be obtained with a prescription, the danger is also reduced by this.

Efficacy Mechanism

The purpose of both Modafinil and Armodafinil is to treat sleep disorders. It follows that it is not surprising that they have some similarities. They share similar pharmacological mechanisms of action that work to promote wakefulness, which is one of their most notable similarities. By interacting with the central nervous system, both produce a wakefulness effect in a similar ways. In order to raise the amount of dopamine in the brain, they each work to inhibit dopamine reuptake by interacting with the dopamine transporter.

Armodafinil vs Modafinil (Mechanism Of Action)

When used to treat sleep disorders, both Armodafinil and Modafinil are effective. According to studies, each one significantly reduced excessive daytime sleepiness and enhanced both wakefulness and sleep quality. The effectiveness, efficiency, and safety of both have been proven.

Side – effects of Armodafinil:

• Blistering, burning, crusting, dryness, or flaking of the skin.
• Difficult or labored breathing.
• Fast, irregular, pounding, or racing heartbeat or pulse.
• Frequent urination.
• Headache, severe and throbbing.
• Increased volume of pale, dilute urine.
• Itching, scaling, severe redness, soreness, or swelling of the skin.

Side-effects of Modafinil:

• Black, tarry stools.
• Blurred vision or other vision changes.
• Chest pain.
• Chills or fever.
• Clumsiness or unsteadiness.
• Dizziness or fainting.
• Increased thirst and urination.
• Mental depression.

REFERENCES:

WHAT IS ARMODAFINIL

WHAT IS MODAFINIL

https://en.wikipedia.org/wiki/Armodafinil

DIFFERENCES

https://www.mayoclinic.org/drugs-supplements/modafinil-oral-route/side-effects/drg-20064870?p=1

WHY DOES MODAFINIL DON’T WORK?

https://modafinil.org/modafinil-not-working/

PRECAUTIONS FOR MODAFINIL

https://www.mayoclinic.org/drugs-supplements/modafinil-oral-route/precautions/drg-20064870?p=1

SIDE-EFFECTS FOR ARMODAFINIL AND MODAFINIL

https://www.mayoclinic.org/drugs-supplements/armodafinil-oral-route/side-effects/drg-20071125?p=1 (FOR ARMODAFINIL)

https://www.mayoclinic.org/drugs-supplements/modafinil-oral-route/side-effects/drg-20064870?p=1 (FOR MODAFINIL)

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